Rui Ju Selected Research

carboxyamido-triazole (carboxyamidotriazole)

2/2022	Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability.
8/2020	Carboxyamidotriazole exerts anti-inflammatory activity in lipopolysaccharide-induced RAW264.7 macrophages by inhibiting NF-κB and MAPKs pathways.
11/2019	Carboxyamidotriazole combined with IDO1-Kyn-AhR pathway inhibitors profoundly enhances cancer immunotherapy.
10/2018	Metabolic Mechanisms and a Rational Combinational Application of Carboxyamidotriazole in Fighting Pancreatic Cancer Progression after Chemotherapy.
4/2017	Therapeutic efficacy of carboxyamidotriazole on 2,4,6-trinitrobenzene sulfonic acid-induced colitis model is associated with the inhibition of NLRP3 inflammasome and NF-κB activation.
4/2017	Carboxyamidotriazole alleviates muscle atrophy in tumor-bearing mice by inhibiting NF-κB and activating SIRT1.
1/2017	Carboxyamidotriazole Synergizes with Sorafenib to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis.
1/2016	Carboxyamidotriazole inhibits oxidative phosphorylation in cancer cells and exerts synergistic anti-cancer effect with glycolysis inhibition.
1/2015	Carboxyamidotriazole: a novel inhibitor of both cAMP-phosphodiesterases and cGMP-phosphodiesterases.
8/2012	Carboxyamidotriazole ameliorates experimental colitis by inhibition of cytokine production, nuclear factor-κB activation, and colonic fibrosis.

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Rui Ju Research Topics

Disease

9	Neoplasms (Cancer) 02/2022 - 05/2012
3	Inflammation (Inflammations) 08/2020 - 05/2012
3	Lewis Lung Carcinoma 04/2017 - 01/2015
2	Colitis 04/2017 - 08/2012
1	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 02/2022
1	Colonic Neoplasms (Colon Cancer) 02/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Hyperandrogenism 11/2021
1	Neoplasm Metastasis (Metastasis) 02/2021
1	Adenoid Cystic Carcinoma (Cylindroma) 02/2021
1	Endometrial Neoplasms (Endometrial Cancer) 01/2021
1	Pelvic Organ Prolapse 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 10/2018
1	Cachexia 04/2017
1	Lung Neoplasms (Lung Cancer) 04/2017
1	Muscular Atrophy (Muscle Atrophy) 04/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2017
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017
1	Lymphoid Leukemia 01/2015
1	Experimental Arthritis 08/2012
1	Fibrosis (Cirrhosis) 08/2012

Drug/Important Bio-Agent (IBA)

11	carboxyamido-triazole (carboxyamidotriazole)IBA 02/2022 - 05/2012
5	Pharmaceutical PreparationsIBA 02/2022 - 01/2015
3	CytokinesIBA 04/2017 - 05/2012
2	Glucose (Dextrose)FDA LinkGeneric 02/2022 - 01/2016
2	Deoxyglucose (2 Deoxy D glucose)IBA 10/2018 - 01/2016
2	Therapeutic UsesIBA 04/2017 - 04/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2017 - 08/2012
2	InterleukinsIBA 04/2017 - 08/2012
1	Biomarkers (Surrogate Marker)IBA 02/2022
1	Glutamine (L-Glutamine)FDA Link 02/2022
1	Anti-Mullerian HormoneIBA 02/2022
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2022
1	Circular RNAIBA 02/2021
1	mahuang-tangIBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Drug CombinationsIBA 11/2019
1	Immune Checkpoint InhibitorsIBA 11/2019
1	InflammasomesIBA 04/2017
1	sym-trinitrobenzeneIBA 04/2017
1	Sulfonic AcidsIBA 04/2017
1	Interleukin-6 (Interleukin 6)IBA 04/2017
1	Interleukin-18 (Interleukin 18)IBA 04/2017
1	Sirtuin 1IBA 04/2017
1	Sorafenib (BAY 43-9006)FDA Link 01/2017
1	polyethylene glycol 400IBA 01/2017
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2016
1	diethylstilbestrol monophosphate (PDES)IBA 01/2015
1	Adenosine (Adenocard)FDA LinkGeneric 01/2015
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2015
1	GuanosineIBA 01/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 08/2012
1	Dextrans (Dextran)FDA Link 08/2012
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 08/2012

Therapy/Procedure

1	Contraception (Birth Control) 11/2021
1	Vaginal Hysterectomy 01/2021
1	Hysterectomy 01/2021
1	Immunotherapy 11/2019
1	Therapeutics 11/2019
1	Drug Therapy (Chemotherapy) 10/2018